Ed uses an iPhone and can control his phone using SIRI. JAWS is definitely the best screen reader however. There's also Zoom Text: it's a screen reader.
Jim is blind and he uses JAWS as a screen reader for his computer. It's not cheap, but your state may have an occupational therapy program that will underwrite the cost. Rich says that there's a home edition for $90 a year. JAWS will read the entire screen and tell you where things are. He says he can do just about anything. There's also ORCA, which is an open-source option.
William is blind and uses a screen reader for his computing, He uses JAWS, but has also used NDVA. But he's having issues subscribing to TWIT's audio feed. Leo says that he'll have his web guy fix the header levels for subscribing.
Jason is looking to get a new laptop and he's thinking of getting a Lenovo. Leo says that it'll be tempting to get a consumer grade model, but Leo advises going with the business-grade ThinkPad line. The keyboards are better, and they are more repairable. Dell is another great option. They have a laptop with a bezel-less screen that is gorgeous. But Jason uses the JAWS screenreader because he's visually impaired, so the screen is not all that important.
Joseph is blind and he uses a screen reader. He wants to customize his Windows sounds, but he is having trouble doing it. Leo says to create day to day limited/standard user accounts to run. If his screen reader needs an administrator level, then that's OK.
Chuck is blind and he wants to get a laptop with a screen reader. Leo says that there are many blind users who are fully functional on a computer. There are braile screens. JAWS is a screen reader, but it's expensive. There's an open source version as well.
Tryell says that Apple has done an outstanding job with accessibility while Google and Microsoft have a lot of work to do. Leo says that Apple is the gold standard on accessibility. The screen reader is great, and it doesn't cost any extra either. So many of those tools are so expensive.
Ed is suffering from macular degeneration. He's color blind and using a computer is getting harder. Leo says making the characters bigger and bigger on the resolution settings. But Ed says he also has Retinitus Pigmentosa, which is like looking through a milky glass, so making the characters larger doesn't help much. At some point, screen readers like JAWS can help. But they're very costly.
Brant's mother is losing her sight and he wants to get voice recognition software to help her. Leo says that screen readers like JAWS can help, but it's expensive. Orca is an open source screen reader. The larger the screen, the better. Try Lighthouse for the Blind or Foundation for the Blind for help. They may even help fund it.