Dana is blind and uses a screen reader. But it won't work with iDrive backup. Leo says that any Windows program should be readable. But it may be that the software uses a picture based text that can't be read by screen readers. It's certainly something that all computer companies should be made aware of.
Dana is also having issues with WinAmp, which is requiring Admin access. It's annoying if you won't want to be in that mode. The issue is more likely with Windows, which is breaking the file associations with WinAmp in order to create an association with Windows' own media player. The good news is, you can turn that feature off in WinAmp. Look for UAC.