Can I replace a failed motherboard in my desktop computer?

Episode 948 (2:26:33)

Michael from Tejunga, CA

Leo says most of his trouble will be with Windows Genuine Advantage, which will think he's installing it on a new computer. He'll have to call Microsoft and let them know he's changed the motherboard. He should also make sure he gets all the drivers he needs before he installs the new motherboard. Then he will install them immediately after booting into safe mode in Windows.