Don is having issues with Malwarebytes. Leo says that if he's experiencing issues with Malwarebytes, there's a good chance that he's been infected. The first thing a malware creator will do is disable online security software and prevent access to those sites in the browser. That's one of the reasons why Leo doesn't like third party antivirus apps. Leo recommends using Microsoft Security Essentials/Windows Defender.
The chatroom pointed to a blogpost at blog.malwarebytes.com, which talks about a bug that Malwarebytes has issued a fix for.